Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells
نویسندگان
چکیده
منابع مشابه
Teratogen screening using transcriptome profiling of differentiating human embryonic stem cells
Teratogens are substances that may cause defects in normal embryonic development while not necessarily being toxic in adults. Identification of possible teratogenic compounds has been historically beset by the species-specific nature of the teratogen response. To examine teratogenic effects on early human development we performed non-biased expression profiling of differentiating human embryoni...
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Human embryonic stem (ES) cells are undifferentiated pluripotent cells derived from the inner cell mass of blastocyst stage embryos. These unique cell lines have the potential to form virtually any cell type in the body and can be propagated in vitro indefinitely in an undifferentiated state. These cells are capable of forming embryoid bodies (EB) that contain cells from all three embryonic lin...
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ژورنال
عنوان ژورنال: Journal of Cellular and Molecular Medicine
سال: 2010
ISSN: 1582-1838
DOI: 10.1111/j.1582-4934.2010.01105.x